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Persistent infection of hepatitis B virus is involved in high rate of p16 methylation in hepatocellular carcinoma

30 Apr 2006

Abstract excerpt

High rate of chronic hepatitis B virus (HBV) infection and p16 promoter methylation were found in the majority of hepatocellular carcinoma (HCC). To investigate the potential linkage between high rate of p16 methylation and HBV infection, p16 methylation was detected with methylation-specific polymerase chain reaction (PCR), and HBV markers were examined with real-time PCR and immunologic method. p16 methylation...

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PMID: 16649250
DOI: 10.1002/mc.20188

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