Article
In vivo phenotyping of the ob/ob mouse by magnetic resonance imaging and 1H-magnetic resonance spectroscopy.
Obesity (Silver Spring, Md.) - 1 Mar 2006
Calderan Laura, Marzola Pasquina, Nicolato Elena, Fabene Paolo F, Milanese Chiara, Bernardi Paolo, Giordano Antonio, Cinti Saverio, Sbarbati Andrea
Abstract excerpt
OBJECTIVE: We studied ob/ob and wild-type (WT) mice to characterize the adipose tissues depots and other visceral organs and to establish an experimental paradigm for in vivo phenotyping. RESEARCH METHODS AND PROCEDURES: An in vivo evaluation was conducted using magnetic resonance imaging and 1H-magnetic resonance spectroscopy (1H-MRS). We used T1-weighted images and three-dimensional spin echo T1-weighted images...
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