Article
Systemic Characterization of an Obese Phenotype in the Zucker Rat Model Defining Metabolic Axes of Energy Metabolism and Host-Microbial Interactions.
Journal of proteome research - 3 Jun 2016
Phetcharaburanin Jutarop, Lees Hannah, Marchesi Julian R, Nicholson Jeremy K, Holmes Elaine, Seyfried Florian, Li Jia V
Abstract excerpt
The Zucker (fa/fa) rat is a valuable and extensively utilized model for obesity research. However, the metabolic networks underlying the systemic response in the obese Zucker rats remain to be elucidated. This information is important to further our understanding of the circulation of the microbial or host-microbial metabolites and their impact on host metabolism. (1)H nuclear magnetic resonance...
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