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Article

Evaluation of replicative capacity and genetic stability of West Nile virus replicons using highly efficient packaging cell lines.

Virology - 20 Jul 2006

Fayzulin Rafik, Scholle Frank, Petrakova Olga, Frolov Ilya, Mason Peter W

Abstract excerpt

A stable cell system for high-efficiency packaging of West Nile virus (WNV) subgenomic replicons into virus-like particles (VLPs) was developed. VLPs could be propagated on these packaging cells and produced infectious foci similar to foci produced by WNV. Focus size correlated with the replicative capacity of WNV replicons, indicating that genome copy number, rather than amount of trans-complementing structural...

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Identifiers

PMID: 16647099
DOI: 10.1016/j.virol.2006.02.036

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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