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Tetracycline-Inducible Packaging Cell Line for Production of Flavivirus Replicon Particles

11 Dec 2003

Abstract excerpt

We have previously developed replicon vectors derived from the Australian flavivirus Kunjin that have a unique noncytopathic nature and have been shown to direct prolonged high-level expression of encoded heterologous genes in vitro and in vivo and to induce strong and long-lasting immune responses to encoded immunogens in mice. To facilitate further applications of these vectors in the form of virus-like...

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PMID: 14671135
DOI: 10.1128/jvi.78.1.531-538.2004

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