Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular cloning and pharmacological characterization of serotonin 5-HT(3A) receptor subtype in dog.

European journal of pharmacology - 24 May 2006

Jensen Thomas N, Nielsen Jacob, Frederiksen Kristen, Ebert Bjarke

Abstract excerpt

In order to establish if the canine 5-hydroxytryptamine type 3A (5-HT(3A)) receptors share the pharmacological profile with human 5-HT(3A) receptors, we cloned and performed a molecular pharmacological characterization of the canine 5-HT(3A) receptor. The 5-HT(3A) cDNA was cloned from canine brain by polymerase chain reaction amplification. It encodes a 483 amino acid peptide that exhibits from 80% (mice) to 90%...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Dogs
Share to Membrane Potentials
Share to Oocytes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Receptors, Serotonin, 5-HT3

Share to Serotonin

Share to Serotonin Antagonists

Share to Serotonin Receptor Agonists

Share to Xenopus

Source

Identifiers

PMID: 16647053
DOI: 10.1016/j.ejphar.2006.03.050

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular cloning and pharmacological characterization of serotonin 5-HT(3A) receptor subtype in dog.PMID 16647053Read ↗

Identification of a domain affecting agonist potency of meta-chlorophenylbiguanide in 5-HT3 receptors.Semantic proximity Read ↗

Sequencing of canine 5-hydroxytriptamine receptor (5-HTR) 1B, 2A, 2C genes and identification of polymorphisms in the 5-HTR1B gene.Semantic proximity Read ↗

Naturally occurring variants in the HTR3B gene significantly alter properties of human heteromeric 5-hydroxytryptamine-3A/B receptorsSemantic proximity Read ↗

The loop C region of the murine 5-HT3A receptor contributes to the differential actions of 5-hydroxytryptamine and m-chlorophenylbiguanide.Semantic proximity Read ↗

Pharmacological differences and similarities between the native mouse 5-HT3 receptor in N1E-115 cells and a cloned short splice variant of the mouse 5-HT3 receptor expressed in HEK 293 cells.Semantic proximity Read ↗

Structure of the human serotonin 5-HT4 receptor gene and cloning of a novel 5-HT4 splice variant.Semantic proximity Read ↗

Differential pharmacology between the guinea-pig and the gorilla 5-HT1D receptor as probed with isochromans (5-HT1D-selective ligands).Semantic proximity Read ↗

The serotonin binding site of human and murine 5-HT2B receptors: molecular modeling and site-directed mutagenesis.Semantic proximity Read ↗

A role for the Val291 residue within the transmembrane domain 2 in diltiazem- and TMB-8 [3,4,5-trimethoxybenzoic acid 8-(diethylamino)octyl ester]-mediated 5-hydroxytryptamine type 3A receptor regulations.Semantic proximity Read ↗

The G protein-coupled receptor subset of the dog genome is more similar to that in humans than rodentsSemantic proximity Read ↗

Serotonin type 3 receptor genes: HTR3A, B, C, D, E.Semantic proximity Read ↗

Heterogeneity amongst 5-HT₃ receptor subunits: is this significant?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.