Article
Genetic changes at the beta-2-adrenergic receptor locus on chromosome 5 in human colorectal carcinomas.
Anticancer research - 1 Jan 2000
Gope R, Gope M L, Thorson A, Christensen M, Smyrk T, Chun M, Alvarez L, Wildrick D M, Boman B M
Abstract excerpt
Matched normal/tumor DNA pairs from 44 colorectal carcinoma patients were examined for tumor-specific genetic changes using a probe for the beta-2-adrenergic receptor (ADRB2R) gene on chromosome 5. This locus (5q31-q32) maps close to the site of chromosomal deletions recently reported to occur in colorectal carcinomas and distal to the chromosomal location of the familial adenomatous polyposis (FAP) gene...
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