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Article

Genetic changes at the beta-2-adrenergic receptor locus on chromosome 5 in human colorectal carcinomas.

Anticancer research - 1 Jan 2000

Gope R, Gope M L, Thorson A, Christensen M, Smyrk T, Chun M, Alvarez L, Wildrick D M, Boman B M

Abstract excerpt

Matched normal/tumor DNA pairs from 44 colorectal carcinoma patients were examined for tumor-specific genetic changes using a probe for the beta-2-adrenergic receptor (ADRB2R) gene on chromosome 5. This locus (5q31-q32) maps close to the site of chromosomal deletions recently reported to occur in colorectal carcinomas and distal to the chromosomal location of the familial adenomatous polyposis (FAP) gene...

Topics

Adenomatous Polyposis Coli
Alleles
Chromosome Deletion
Chromosomes, Human, Pair 5
Colorectal Neoplasms
Humans
Receptors, Adrenergic, beta

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 1663718

Genes

FAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1663718-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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