Article
Prediction of IBD based on population history for fine gene mapping.
Genetics, selection, evolution : GSE - 1 Jan 2000
Hernández-Sánchez Jules, Haley Chris S, Woolliams John A
Abstract excerpt
A novel multiple regression method (RM) is developed to predict identity-by-descent probabilities at a locus L (IBDL), among individuals without pedigree, given information on surrounding markers and population history. These IBDL probabilities are a function of the increase in linkage disequilibrium (LD) generated by drift in a homogeneous population over generations. Three parameters are sufficient to describe...
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