Article
Immune surveillance in multiple sclerosis patients treated with natalizumab.
Annals of neurology - 1 May 2006
Stüve Olaf, Marra Christina M, Jerome Keith R, Cook Linda, Cravens Petra D, Cepok Sabine, Frohman Elliot M, Phillips J Theodore, Arendt Gabriele, Hemmer Bernhard, Monson Nancy L, Racke Michael K
Abstract excerpt
OBJECTIVE: Our objective was to test whether natalizumab, an antibody against very late activating antigen (VLA)-4, interferes with central nervous system immune surveillance as assessed by leukocyte cell numbers and cellular phenotypes in cerebrospinal fluid (CSF) and peripheral blood. METHODS:...
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