Article
Skewing towards neuroendocrine phenotype in high grade or high stage androgen-responsive primary prostate cancer.
European urology - 1 Aug 2005
Puccetti Luca, Supuran Claudiu T, Fasolo Pier P, Conti Enrico, Sebastiani Giancarlo, Lacquaniti Sergio, Mandras Roberto, Milazzo Maria G, Dogliani Natalia, De Giuli Paolo, Fasolis Giuseppe
Abstract excerpt
OBJECTIVE: The prognostic influence of neuroendocrine (NE) differentiation in prostate cancer patients is not yet properly established. In a series of primary hormone-naive prostate cancers from a patient population that underwent radical prostatectomy, we wanted to determine the relationship between NE phenotype expression and Gleason sum, disease stage, and serum PSA concentration. METHODS: Chromogranin A (CgA)...
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