Article
ALDH2 promoter polymorphism has no effect on the risk for alcoholism.
Alcohol and alcoholism (Oxford, Oxfordshire) - 1 Jan 2000
Kimura Mitsuru, Kimura Shigeko, Matsushita Sachio, Kashima Haruo, Higuchi Susumu
Abstract excerpt
AIM: To test for the possible association between mitochondrial aldehyde dehydrogenase (ALDH2) promoter polymorphism and alcoholism. METHODS: Genotyping to identify the polymorphisms in 515 alcoholic patients and 361 normal controls was performed. RESULTS: There were no significant differences between the genotype and allele frequencies of the -357A/G polymorphism in alcoholics and normal controls. Linkage...
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