Article
ATM haplotypes and breast cancer risk in Jewish high-risk women.
British journal of cancer - 22 May 2006
Koren M, Kimmel G, Ben-Asher E, Gal I, Papa M Z, Beckmann J S, Lancet D, Shamir R, Friedman E
Abstract excerpt
While genetic factors clearly play a role in conferring breast cancer risk, the contribution of ATM gene mutations to breast cancer is still unsettled. To shed light on this issue, ATM haplotypes were constructed using eight SNPs spanning the ATM gene region (142 kb) in ethnically diverse non-Ashkenazi Jewish controls (n=118) and high-risk (n=142) women. Of the 28 haplotypes noted, four were encountered in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
