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Article

Population-based estimates of age-specific cumulative risk of breast cancer for pathogenic variants in ATM.

Breast cancer research : BCR - 1 Apr 2022

Renault Anne-Laure, Dowty James G, Steen Jason A, Li Shuai, Winship Ingrid M, Giles Graham G, Hopper John L, Southey Melissa C, Nguyen-Dumont Tú

Abstract excerpt

BACKGROUND: Multigene panel tests for breast cancer predisposition routinely include ATM as it is now a well-established breast cancer predisposition gene. METHODS: We included ATM in a multigene panel test applied to the Australian Breast Cancer Family Registry (ABCFR), a population-based case-control-family study of breast cancer, with the purpose of estimating the prevalence and penetrance of heterozygous ATM...

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Source

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Identifiers

PMID: 35365198
DOI: 10.1186/s13058-022-01518-y
PMCID: PMC8973562

Genes

ATM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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