Article
Nisin induction without nisin secretion.
Microbiology (Reading, England) - 1 May 2006
Hilmi Hanan T Abbas, Kylä-Nikkilä Kari, Ra Runar, Saris Per E J
Abstract excerpt
Nisin Z, a post-translationally modified antimicrobial peptide of Lactococcus lactis, is positively autoregulated by extracellular nisin via the two-component regulatory proteins NisRK. A mutation in the nisin NisT transporter rendered L. lactis incapable of nisin secretion, and nisin accumulated inside the cells. Normally nisin is activated after secretion by the serine protease NisP in the cell wall. This study...
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