Article
Murine model of immune-mediated rejection of the acute lymphoblastic leukemia 70Z/3.
Journal of immunology (Baltimore, Md. : 1950) - 1 May 2006
Labbe Alain, Tran Anne H, Paige Christopher J
Abstract excerpt
70Z/3 is a murine pre-B cell leukemia line derived from BDF(1) mice and has been used in the study of signaling pathways in B cells. 70Z/3 cells were initially found to cause widespread disease upon injections in animals. We have isolated 70Z/3 variants divergent in their capacity to lead to morbidity after injections. One variant, 70Z/3-NL, elicits an immune response protecting the animal from tumor growth....
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