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Article

Modulation of Alp4 function in Schizosaccharomyces pombe induces novel phenotypes that imply distinct functions for nuclear and cytoplasmic gamma-tubulin complexes.

Genes to cells : devoted to molecular & cellular mechanisms - 1 Apr 2006

Masuda Hirohisa, Toda Takashi, Miyamoto Rumi, Haraguchi Tokuko, Hiraoka Yasushi

Abstract excerpt

The gamma-tubulin complex acts as a nucleation unit for microtubule assembly. It remains unknown, however, how spatial and temporal regulation of the complex activity affects microtubule-mediated cellular processes. Alp4 is one of the essential components of the S. pombe gamma-tubulin complex. We show here that overproduction of a carboxy-terminal form of Alp4 (Alp4C) and its derivatives tagged to a nuclear...

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Identifiers

PMID: 16611237
DOI: 10.1111/j.1365-2443.2006.00946.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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