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Article

Conditional mutations in gamma-tubulin reveal its involvement in chromosome segregation and cytokinesis.

Molecular biology of the cell - 1 Aug 2001

Hendrickson T W, Yao J, Bhadury S, Corbett A H, Joshi H C

Abstract excerpt

gamma-Tubulin is a conserved essential protein required for assembly and function of the mitotic spindle in humans and yeast. For example, human gamma-tubulin can replace the gamma-tubulin gene in Schizosaccharomyces pombe. To understand the structural/functional domains of gamma-tubulin, we performed a systematic alanine-scanning mutagenesis of human gamma-tubulin (TUBG1) and studied phenotypes of each mutant...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 11514629
DOI: 10.1091/mbc.12.8.2469
PMCID: PMC58607

Genes

TUBG1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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