Article
Urine steroid hormone profile analysis in cytochrome P450 oxidoreductase deficiency: implication for the backdoor pathway to dihydrotestosterone.
The Journal of clinical endocrinology and metabolism - 1 Jul 2006
Homma Keiko, Hasegawa Tomonobu, Nagai Toshiro, Adachi Masanori, Horikawa Reiko, Fujiwara Ikuma, Tajima Toshihiro, Takeda Ryoujun, Fukami Maki, Ogata Tsutomu
Abstract excerpt
CONTEXT: Although the "backdoor" pathway to dihydrotestosterone has been postulated in the fetal-to-early-infantile period of patients with cytochrome P450 oxidoreductase deficiency (PORD), clinical data in support of this pathway remain limited. OBJECTIVE: The objective of this study was to obtain clinical evidence for the presence of the backdoor pathway in PORD. SETTING: This was a collaboration study between...
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