Article
Single nucleotide polymorphisms and haplotypes of protein C and protein S genes in the Thai population.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Jan 2006
Chumpia Worawan, Peerapittayamongkol Chayanon, Angchaisuksiri Pantep, Komanasin Nantarat, Muta Koichiro, Kuaha Kunnika, Iida Hiroko, Inoue Sumiko, Wada Yui, Kurihara Masako, Hamasaki Naotaka, Fucharoen Suthat
Abstract excerpt
Protein C (PC) and protein S (PS) play key roles in an anticoagulant pathway in order to control the haemostatic system. We identified single nucleotide polymorphisms (SNPs) and/or haplotypes in the promotor and exons of the whole PC and PS genes and in the 3'-untranslated region of the PS gene in 55 Thai individuals. The PC gene revealed 10 haplotypes. One synonymous SNP at 2196 was found in the normal Thai...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
