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Article

Canonical Single Nucleotide Polymorphisms (SNPs) for High-Resolution Subtyping of Shiga-Toxin Producing Escherichia coli (STEC) O157:H7.

PloS one - 1 Jan 2015

Griffing Sean M, MacCannell Duncan R, Schmidtke Amber J, Freeman Molly M, Hyytiä-Trees Eija, Gerner-Smidt Peter, Ribot Efrain M, Bono James L

Abstract excerpt

The objective of this study was to develop a canonical, parsimoniously-informative SNP panel for subtyping Shiga-toxin producing Escherichia coli (STEC) O157:H7 that would be consistent with epidemiological, PFGE, and MLVA clustering of human specimens. Our group had previously identified 906 putative discriminatory SNPs, which were pared down to 391 SNPs based on their prevalence in a test set. The 391 SNPs were...

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PMID: 26132731
DOI: 10.1371/journal.pone.0131967
PMCID: PMC4488506

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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