Population structure and genetic diversity of non-O157 Shiga toxin-producing Escherichia coli (STEC) clinical isolates from Michigan.

doi:10.1038/s41598-021-83775-z

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Article

Population structure and genetic diversity of non-O157 Shiga toxin-producing Escherichia coli (STEC) clinical isolates from Michigan.

Scientific reports - 24 Feb 2021

Blankenship Heather M, Mosci Rebekah E, Dietrich Stephen, Burgess Elizabeth, Wholehan Jason, McWilliams Karen, Pietrzen Karen, Benko Scott, Gatesy Ted, Rudrik James T, Soehnlen Marty, Manning Shannon D

Abstract excerpt

Non-O157 STEC are increasingly linked to foodborne infections, yet little is known about the diversity and molecular epidemiology across locations. Herein, we used whole genome sequencing to examine genetic variation in 894 isolates collected from Michigan patients between 2001 and 2018. In all, 67 serotypes representing 69 multilocus sequence types were identified. Serotype diversity increased from an average of...

Topics

Adolescent
Adult
Aged
Aged, 80 and over
Child
Child, Preschool
Escherichia coli Infections
Escherichia coli O157
Escherichia coli Proteins
Female

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genetic Variation

Humans

Infant

Infant, Newborn

Male

Michigan

Middle Aged

Molecular Epidemiology

Source

Open in PubMed Open full text

Identifiers

PMID: 33627701
DOI: 10.1038/s41598-021-83775-z
PMCID: PMC7904848

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