Article
Phylogeny of Shiga toxin-producing Escherichia coli O157 isolated from cattle and clinically ill humans.
Molecular biology and evolution - 1 Aug 2012
Bono James L, Smith Timothy P L, Keen James E, Harhay Gregory P, McDaneld Tara G, Mandrell Robert E, Jung Woo Kyung, Besser Thomas E, Gerner-Smidt Peter, Bielaszewska Martina, Karch Helge, Clawson Michael L
Abstract excerpt
Cattle are a major reservoir for Shiga toxin-producing Escherichia coli O157 (STEC O157) and harbor multiple genetic subtypes that do not all associate with human disease. STEC O157 evolved from an E. coli O55:H7 progenitor; however, a lack of genome sequence has hindered investigations on the divergence of human- and/or cattle-associated subtypes. Our goals were to 1) identify nucleotide polymorphisms for STEC...
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