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Article

Analysis of 14 LRRK2 mutations in Parkinson's plus syndromes and late‐onset Parkinson's disease

6 Apr 2006

Abstract excerpt

The pleomorphic pathology of postmortem LRRK2-positive patients and the frequent association with late-onset Parkinson's disease (LOPD) symptoms suggest that LRRK2 mutations may play a role in Parkinson's Plus disorders and LOPD. Published studies primarily focus on the common G2019S mutation. Analysis of a spectrum of LRRK2 mutations in Parkinson's Plus disorders has yet to be reported. We investigated 14...

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Identifiers

PMID: 16602113
DOI: 10.1002/mds.20875

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