Article
Sequence variation in the T-cell epitopes of the Plasmodium falciparum circumsporozoite protein among field isolates is temporally stable: a 5-year longitudinal study in southern Vietnam.
Journal of clinical microbiology - 1 Apr 2006
Jalloh Amadu, van Thien Huynh, Ferreira Marcelo U, Ohashi Jun, Matsuoka Hiroyuki, Kanbe Toshio, Kikuchi Akihiko, Kawamoto Fumihiko
Abstract excerpt
In an effort to decipher the nature and extent of antigen polymorphisms of malaria parasites in a setting where malaria is hypomesoendemic, we conducted a 5-year longitudinal study (1998 to 2003) by sequencing the Th2R and Th3R epitopes of the circumsporozoite protein (CSP) of 142 Plasmodium falciparum field isolates from Bao Loc, Vietnam. Samples were collected during the high-transmission season, September...
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