Article
Monitoring of WT1-specific cytotoxic T lymphocytes after allogeneic hematopoietic stem cell transplantation.
International journal of cancer - 15 Sept 2006
Morita Yuriko, Heike Yuji, Kawakami Mami, Miura Osamu, Nakatsuka Shin-Ichi, Ebisawa Michiko, Mori Shin-Ichiro, Tanosaki Ryuji, Fukuda Takahiro, Kim Sung-Won, Tobinai Kensei, Takaue Yoichi
Abstract excerpt
Donor-derived cytotoxic T lymphocytes (CTL) that respond to tumor antigens emerge after hematopoietic stem cell transplantation (HSCT), particularly in association with the status of immune recovery. To analyze the frequency of CTL against PR1, PRAME and WT1 after HSCT, a tetramer-based analysis was performed in 97 samples taken from 35 patients (9 AML, 11 MDS, 2 CML, 4 ALL, 7 lymphoma and 2 renal cell carcinoma...
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