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Article

Effects of mechanical loading on intervertebral disc metabolism in vivo.

The Journal of bone and joint surgery. American volume - 1 Apr 2006

Iatridis James C, MacLean Jeffrey J, Roughley Peter J, Alini Mauro

Abstract excerpt

The overall goal of this work is to define more clearly which mechanical loading conditions are associated with accelerated disc degeneration. This article briefly reviews recent studies describing the effects of mechanical loading on the metabolism of intervertebral disc cells and defines hypothetical models that provide a framework for quantitative relationships between mechanical loading and disc-cell...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 16595442
DOI: 10.2106/JBJS.E.01407
PMCID: PMC3697474

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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