Article
The contributions of normal variation and genetic background to mammalian gene expression.
Genome biology - 1 Jan 2006
Pritchard Colin, Coil David, Hawley Sarah, Hsu Li, Nelson Peter S
Abstract excerpt
BACKGROUND: Qualitative and quantitative variability in gene expression represents the substrate for external conditions to exert selective pressures for natural selection. Current technologies allow for some forms of genetic variation, such as DNA mutations and polymorphisms, to be determined accurately on a comprehensive scale. Other components of variability, such as stochastic events in cellular...
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