Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

cDNA clones of Japanese hepatitis C virus genomes derived from a single patient show sequence heterogeneity.

The Journal of general virology - 1 Nov 1991

Oshima M, Tsuchiya M, Yagasaki M, Orita T, Hasegawa M, Tomonoh K, Kojima T, Hirata Y, Yamamoto O, Sho Y

Abstract excerpt

Twelve cDNA clones of Japanese hepatitis C virus (HCV) have been isolated from liver tissue of a single non-A, non-B hepatitis patient. These clones represented the non-structural domains of HCV. The degree of substitution in the nucleotide sequences and deduced amino acid sequences between these clones was 9.5 and 7.7%, respectively. This high level of substitution suggested that repeated infections of different...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Base Sequence

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cloning, Molecular

Share to DNA, Viral

Share to Genetic Variation

Share to Molecular Sequence Data

Share to Sequence Homology, Nucleic Acid

Source

Identifiers

PMID: 1658209
DOI: 10.1099/0022-1317-72-11-2805

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

cDNA clones of Japanese hepatitis C virus genomes derived from a single patient show sequence heterogeneity.PMID 1658209Read ↗

Sequence diversity of hepatitis C viral genomes.Semantic proximity Read ↗

Molecular cloning of hepatitis C virus genome from a single Japanese carrier: sequence variation within the same individual and among infected individuals.Semantic proximity Read ↗

Molecular cloning of the human hepatitis C virus genome from Japanese patients with non-A, non-B hepatitis.Semantic proximity Read ↗

Marked sequence diversity in the putative envelope proteins of hepatitis C viruses.Semantic proximity Read ↗

Heterogeneity within the nonstructural protein 5-encoding region of hepatitis C viruses from a single patient.Semantic proximity Read ↗

Genetic variability and characterization of non-structural region 5 of hepatitis C virus genome from Chinese patients.Semantic proximity Read ↗

Full-length sequence of a hepatitis C virus genome having poor homology to reported isolates: comparative study of four distinct genotypes.Semantic proximity Read ↗

Genomic characterization and mutation rate of hepatitis C virus isolated from a patient who contracted hepatitis during an epidemic of non-A, non-B hepatitis in Japan.Semantic proximity Read ↗

Nucleotide sequence of the 5' noncoding region of hepatitis G virus isolated from Japanese patients: comparison with reported isolates.Semantic proximity Read ↗

Nucleotide sequence of hepatitis C virus (type 3b) isolated from a Japanese patient with chronic hepatitis C.Semantic proximity Read ↗

An infectious molecular clone of a Japanese genotype 1b hepatitis C virus.Semantic proximity Read ↗

A second group of hepatitis C viruses.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.