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Article

A chemokine-binding domain in the tumor necrosis factor receptor from variola (smallpox) virus

31 Mar 2006

Abstract excerpt

Variola virus (VaV) is the causative agent of smallpox, one of the most devastating diseases encountered by man, that was eradicated in 1980. The deliberate release of VaV would have catastrophic consequences on global public health. However, the mechanisms that contribute to smallpox pathogenesis are poorly understood at the molecular level. The ability of viruses to evade the host defense mechanisms is an...

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PMID: 16581912
DOI: 10.1073/pnas.0510462103

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