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Article

CrmE, a Novel Soluble Tumor Necrosis Factor Receptor Encoded by Poxviruses

1 Jan 2001

Abstract excerpt

Cytokines and chemokines play a critical role in both the innate and acquired immune responses and constitute prime targets for pathogen sabotage. Molecular mimicry of cytokines and cytokine receptors is a mechanism encoded by large DNA viruses to modulate the host immune response. Three tumor necrosis factor receptors (TNFRs) have been identified in the poxvirus cowpox virus. Here we report the identification...

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PMID: 11119592
DOI: 10.1128/jvi.75.1.226-233.2001

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