Article
Loss of glial lazarillo, a homolog of apolipoprotein D, reduces lifespan and stress resistance in Drosophila.
Current biology : CB - 4 Apr 2006
Sanchez Diego, López-Arias Begoña, Torroja Laura, Canal Inmaculada, Wang Xiaohui, Bastiani Michael J, Ganfornina Maria D
Abstract excerpt
The vertebrate Apolipoprotein D (ApoD) is a lipocalin secreted from subsets of neurons and glia during neural development and aging . A strong correlation exists between ApoD overexpression and numerous nervous system pathologies as well as obesity, diabetes, and many forms of cancer . However, the exact relationship between the function of ApoD and the pathophysiology of these diseases is still unknown. We have...
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