Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Ensheathing glia promote increased lifespan and healthy brain aging

24 Feb 2023

Abstract excerpt

Glia have an emergent role in brain aging and disease. In the Drosophila melanogaster brain, ensheathing glia function as phagocytic cells and respond to acute neuronal damage, analogous to mammalian microglia. We previously reported changes in glia composition over the life of ants and fruit flies, including a decline in the relative proportion of ensheathing glia with time. How these changes influence brain...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer's disease research and treatments
Share to Genetics, Aging, and Longevity in Model Organisms
Share to Neuroinflammation and Neurodegeneration Mechanisms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36840361
DOI: 10.1111/acel.13803

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Ensheathing glia promote increased lifespan and healthy brain agingPMID 36840361Read ↗

Sleep rescues age-associated loss of glial engulfmentSemantic proximity Read ↗

Senescent glia link mitochondrial dysfunction and lipid accumulationSemantic proximity Read ↗

Drosophilaas a model to study the role of glia in neurodegenerationSemantic proximity Read ↗

Age-related loss of brain demyelinating and remyelinating potential is overcome by microglia renewalSemantic proximity Read ↗

Surface glia predominantly contribute to the development of ALS/FTD in Drosophila modelSemantic proximity Read ↗

Drosophila Glia: Models for Human Neurodevelopmental and Neurodegenerative DisordersSemantic proximity Read ↗

Loss of glia-neuronal interactions and age-dependent cell death in a <i>Drosophila</i> model of adult neurodegenerationSemantic proximity Read ↗

Recent insights into the role of glia and oxidative stress in Alzheimer's disease gained from DrosophilaSemantic proximity Read ↗

Senescent glia spell trouble in Alzheimer’s diseaseSemantic proximity Read ↗

Impairment of the glial phagolysosomal system drives prion-like propagation in a <i>Drosophila</i> model of Huntington’s diseaseSemantic proximity Read ↗

miR-31 mutants reveal continuous glial homeostasis in the adult Drosophila brain.Semantic proximity Read ↗

Surface glia predominantly contribute to the development of ALS/FTD in <i>Drosophila</i> modelSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.