Article
Detecting the cytogenetic effects in workers occupationally exposed to vincristine with four genetic tests.
Mutation research - 25 Jul 2006
Hongping Deng, Jianlin Lou, Meibian Zhang, Wei Wu, Lifen Jin, Shijie Chen, Wei Zheng, Baohong Wang, Jiliang He
Abstract excerpt
To study the human genetic damage induced by vincristine (VCR), the cytogenetic effects in workers occupationally exposed to vincristine were studied with micronucleus (MN) test, comet assay, hypoxantinepho-guanine phosphoribosyl-transferase (hprt) gene mutation assay and T-cells receptor (TCR) gene mutation assay. Fresh peripheral blood samples were collected from the workers and controls. Fifteen workers from a...
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