Conjugal transfer of antibiotic resistance factors in Bacteroides fragilis: the btgA and btgB genes of plasmid pBFTM10 are required for its transfer from Bacteroides fragilis and for its mobilization by IncP beta plasmid R751 in Escherichia coli.

doi:10.1128/jb.173.23.7471-7480.1991

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Article

Conjugal transfer of antibiotic resistance factors in Bacteroides fragilis: the btgA and btgB genes of plasmid pBFTM10 are required for its transfer from Bacteroides fragilis and for its mobilization by IncP beta plasmid R751 in Escherichia coli.

Journal of bacteriology - 1 Dec 1991

Hecht D W, Jagielo T J, Malamy M H

Abstract excerpt

Transferable plasmids play an important role in the dissemination of clindamycin-erythromycin resistance in Bacteroides fragilis. We previously described the isolation and properties of pBFTM10, a 14.9-kb ClnR transfer factor from B. fragilis TMP10. We also reported the isolation of a transfer-deficient deletion derivative of pBFTM10 contained in the B. fragilis-Escherichia coli shuttle vector pGAT400. In the...

Topics

Amino Acid Sequence
Bacterial Proteins
Bacteroides fragilis
Base Sequence
Chromosome Deletion
Clindamycin
Conjugation, Genetic
DNA Transposable Elements
DNA, Bacterial
Drug Resistance, Microbial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Erythromycin

Escherichia coli

Genes, Bacterial

Molecular Sequence Data

Mutagenesis, Insertional

Phenotype

Plasmids

Protein Biosynthesis

Source

Open in PubMed Open full text

Identifiers

PMID: 1657890
DOI: 10.1128/jb.173.23.7471-7480.1991
PMCID: PMC212512

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1657890-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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