Article
Heteroduplex DNA formation is associated with replication and recombination in poxvirus-infected cells.
Genetics - 1 Sept 1991
Fisher C, Parks R J, Lauzon M L, Evans D H
Abstract excerpt
Poxviruses are large DNA viruses that replicate in the cytoplasm of infected cells and recombine at high frequencies. Calcium phosphate precipitates were used to cotransfect Shope fibroma virus-infected cells with different DNA substrates and the recombinant products assayed by genetic and bioche...
Topics
- Bacteriophage lambda
- Blotting, Southern
- Cells, Cultured
- DNA Repair
- DNA Replication
- DNA-Directed DNA Polymerase
- Electrophoresis
- Escherichia coli
- Fibroma Virus, Rabbit
- HeLa Cells
- Humans
- Kinetics
- Mutation
- Nucleic Acid Heteroduplexes
- Plasmids
- Recombination, Genetic
- Transfection