Article
The di-leucine motif contributes to class a scavenger receptor-mediated internalization of acetylated lipoproteins.
Arteriosclerosis, thrombosis, and vascular biology - 1 Jun 2006
Chen Yaoyu, Wang Xiaohua, Ben Jingjing, Yue Shen, Bai Hui, Guan Xiaoxiang, Bai Xiaoming, Jiang Li, Ji Yong, Fan Leming, Chen Qi
Abstract excerpt
OBJECTIVE: The di-leucine motif exists in the intracellular domains of certain cell surface receptors, participating in the receptor-mediated endocytosis. The present study was aimed at determining the role of the di-leucine motif in class A scavenger receptor (SR-A)-mediated ligand endocytosis. METHODS AND RESULTS: cDNA coding for a mutant (SR-A mutant N3132LM) with deletion of the di-leucine structure was...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
