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Article

Thioredoxin is required for deoxyribonucleotide pool maintenance during S phase.

The Journal of biological chemistry - 2 Jun 2006

Koc Ahmet, Mathews Christopher K, Wheeler Linda J, Gross Michael K, Merrill Gary F

Abstract excerpt

Thioredoxin was initially identified by its ability to serve as an electron donor for ribonucleotide reductase in vitro. Whether it serves a similar function in vivo is unclear. In Saccharomyces cerevisiae, it was previously shown that Deltatrx1 Deltatrx2 mutants lacking the two genes for cytosolic thioredoxin have a slower growth rate because of a longer S phase, but the basis for S phase elongation was not...

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Identifiers

PMID: 16574642
DOI: 10.1074/jbc.M601968200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Thioredoxin is required for deoxyribonucleotide pool maintenance during S phase.PMID 16574642Read ↗

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