Article
Hepatitogenicity of three plaque purified mutants of hepatotropic mouse hepatitis virus, MHV-2.
The Journal of veterinary medical science - 1 Aug 1991
Goto N, Kyo M, Kang J K, Uchida K, Xu D L, Kai K
Abstract excerpt
Hepatitogenicity of three plaque purified mutant strains of mouse hepatitis virus, designated as MHV-2S, -2M and -2L, isolated from MHV-2 infected SR-CDF1-DBT cells was studied. After intraperitoneal inoculation with 2 x 10(5) PFU of parental MHV-2 and its mutants to 4-week-old female ICR mice, 4...
Topics
- Animals
- Endoplasmic Reticulum
- Female
- Fluorescent Antibody Technique
- Golgi Apparatus
- Hepatitis, Viral, Animal
- Liver
- Mice
- Mice, Inbred ICR
- Microscopy, Electron
- Murine hepatitis virus
- Mutation
- Necrosis
- Specific Pathogen-Free Organisms
- Virion