Article
The neuropathologic phenotype of experimental ovine BSE is maintained after blood transfusion.
Blood - 15 Jul 2006
Sisó Sílvia, González Lorenzo, Houston Fiona, Hunter Nora, Martin Stuart, Jeffrey Martin
Abstract excerpt
Iatrogenic transmission by blood transfusion has been described in cases of human variant Creutzfeldt-Jakob disease (vCJD), experimental ovine bovine spongiform encephalopathy (BSE), and natural sheep scrapie, demonstrating that blood in these prion diseases is infectious. However, the possible effect of the transfusion, derived from differences in the inoculum (blood) and the route of infection (intravenous), on...
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