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Article

No major change in vCJD agent strain after secondary transmission via blood transfusion.

PloS one - 6 Aug 2008

Bishop Matthew T, Ritchie Diane L, Will Robert G, Ironside James W, Head Mark W, Thomson Val, Bruce Moira, Manson Jean C

Abstract excerpt

BACKGROUND: The identification of transmission of variant Creutzfeldt-Jakob disease (vCJD) by blood transfusion has prompted investigation to establish whether there has been any alteration in the vCJD agent following this route of secondary transmission. Any increase in virulence or host adaptation would require a reassessment of the risk analyses relating to the possibility of a significant secondary outbreak...

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Identifiers

PMID: 18682737
DOI: 10.1371/journal.pone.0002878
PMCID: PMC2478718

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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