Article
Phenotype of disease-associated PrP accumulation in the brain of bovine spongiform encephalopathy experimentally infected sheep.
The Journal of general virology - 1 Mar 2005
González Lorenzo, Martin Stuart, Houston Fiona E, Hunter Nora, Reid Hugh W, Bellworthy Sue J, Jeffrey Martin
Abstract excerpt
In view of the established link between bovine spongiform encephalopathy (BSE) and variant Creutzfeldt-Jakob disease and of the susceptibility of sheep to experimental BSE, the detection of potential cases of naturally occurring BSE in sheep has become of great importance. In this study, the immunohistochemical (IHC) phenotype of disease-associated prion protein (PrP(d)) accumulation has been determined in the...
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