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Drug resistance and neurotransmitter receptors of nematodes: recent studies on the mode of action of levamisole

1 Oct 2005

Abstract excerpt

Here we review recent studies on the mode of action of the cholinergic anthelmintics (levamisole, pyrantel etc.). We also include material from studies on the free living nematode Caenorhabditis elegans. The initial notion that these drugs act on a single receptor population, while attractive, has proven to be an oversimplification. In both free living and parasitic nematodes there are multiple types of nicotinic...

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PMID: 16569294
DOI: 10.1017/s0031182005008668

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