Article
Genetic diversity of levamisole receptor subunits in parasitic nematode species and abbreviated transcripts associated with resistance.
Pharmacogenetics and genomics - 1 Jul 2010
Neveu Cédric, Charvet Claude L, Fauvin Aymeric, Cortet Jacques, Beech Robin N, Cabaret Jacques
Abstract excerpt
OBJECTIVES: The molecular mechanisms of levamisole (LEV) activity and expression of resistance remain largely unknown in parasitic nematodes. In contrast, genetic screens for mutants that survive exposure to LEV in the free-living nematode Caenorhabditis elegans have led to the identification of...
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