Article

Favorable efficacy of rituximab in ANCA-associated vasculitis patients with excessive B cell differentiation

2020-04-29

Abstract excerpt

<title>Abstract</title> <p><bold>Objectives: </bold>B-cell depletion by rituximab (RTX) is an effective treatment for anti-neutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis (AAV). However, peripheral B cell phenotypes and the selection criteria for RTX therapy in AAV remain unclear.<bold>Methods:</bold> Phenotypic characterization of circulating B cells was performed by 8-color flow cytometric anal...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 435985a1-14c6-5085-aa96-1ad9c08102d3
DOI: 10.21203/rs.2.23827/v2

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Favorable efficacy of rituximab in ANCA-associated vasculitis patients with excessive B cell differentiationDOI 10.21203/rs.2.23827/v2Read

Significant association between clinical characteristics and immuno-phenotypes in patients with ANCA-associated vasculitisSemantic proximity Read

Altered B cells homeostasis in child-onset immunoglobulin A vasculitisSemantic proximity Read

Decreased CD5⁺ B cells in active ANCA vasculitis and relapse after rituximab.Semantic proximity Read

Classification of ANCA-associated vasculitis: differences based on ANCA specificity and clinicopathologic phenotype.Semantic proximity Read

Longitudinal monitoring of circulating immune cell phenotypes in anti-neutrophil cytoplasmic antibody-associated vasculitis.Semantic proximity Read

Heterogeneity and individualized therapy for eosinophilic granulomatosis with polyangiitis.Semantic proximity Read

Real-World Effectiveness and Safety of Avacopan in ANCA-Associated Vasculitis: A Systematic Literature Review and Meta-analysisSemantic proximity Read

Severe infections in patients with anti-neutrophil cytoplasmic antibody-associated vasculitis: a retrospective cohort study with a clinical phenotype approach.Semantic proximity Read

Rituximab in Systemic Lupus Erythematosus: Transient Effects on Autoimmunity Associated Lymphocyte Phenotypes and Implications for Immunogenicity.Semantic proximity Read

Type of ANCA may be Superior to Clinical Phenotype in Distinguishing Different Clinical Entities in ANCA-associated VasculitisSemantic proximity Read

Patterns of ANA+ B cells for SLE patient stratificationSemantic proximity Read

Antineutrophil cytoplasmic antibody-associated vasculitis classification by cluster analysis based on clinical phenotypes: a single-center retrospective cohort study.Semantic proximity Read