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Article

Dynamic polymorphism of Ras observed by single molecule FRET is the basis for molecular recognition.

Biochemical and biophysical research communications - 12 May 2006

Arai Yoshiyuki, Iwane Atsuko Hikikoshi, Wazawa Tetsuichi, Yokota Hiroaki, Ishii Yoshiharu, Kataoka Tohru, Yanagida Toshio

Abstract excerpt

Ras regulates signal transduction pathway function by dynamically interacting with various effectors. To understand the basis for Ras function, its conformational dynamics were measured in the absence and presence of effectors using single molecule fluorescence resonance energy transfer (FRET) between probes located on the Switch II region and GTP. The time trajectories of FRET efficiency from GTP-bound Ras...

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PMID: 16564025
DOI: 10.1016/j.bbrc.2006.03.031

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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