Article
The ability of pseudorabies virus to grow in different hosts is affected by the duplication and translocation of sequences from the left end of the genome to the UL-US junction.
Journal of virology - 1 Nov 1991
Reilly L M, Rall G, Lomniczi B, Mettenleiter T C, Kuperschmidt S, Ben-Porat T
Abstract excerpt
Pseudorabies virus is a herpesvirus which has a class 2 genome. However, under certain growth conditions it acquires a genome with class 3-like characteristics. In these variants, the leftmost sequences of the long (L) component of the viral genome have been duplicated and translocated to the rig...
Topics
- Animals
- Base Sequence
- Blotting, Southern
- Cells, Cultured
- Chick Embryo
- Chickens
- Chromosome Deletion
- Cloning, Molecular
- DNA, Viral
- Fibroblasts
- Genetic Variation
- Genome, Viral
- Herpesvirus 1, Suid
- Mice
- Mutation