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Article

Establishment of an in vitro system representing the chicken gut-associated lymphoid tissue.

PloS one - 1 Jan 2012

Alitheen Noorjahan Banu, McClure Susan Jane, Yeap Swee Keong, Kristeen-Teo Ye Wen, Tan Sheau Wei, McCullagh Peter

Abstract excerpt

The bursa of Fabricius is critical for B cell development and differentiation in chick embryos. This study describes the production in vitro, from dissociated cell suspensions, of cellular agglomerates with functional similarities to the chicken bursa. Co-cultivation of epithelial and lymphoid cells obtained from embryos at the appropriate developmental stage regularly led to agglomerate formation within 48...

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Identifiers

PMID: 23185307
DOI: 10.1371/journal.pone.0049188
PMCID: PMC3501491

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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