Article
Establishment of an in vitro system representing the chicken gut-associated lymphoid tissue.
PloS one - 1 Jan 2012
Alitheen Noorjahan Banu, McClure Susan Jane, Yeap Swee Keong, Kristeen-Teo Ye Wen, Tan Sheau Wei, McCullagh Peter
Abstract excerpt
The bursa of Fabricius is critical for B cell development and differentiation in chick embryos. This study describes the production in vitro, from dissociated cell suspensions, of cellular agglomerates with functional similarities to the chicken bursa. Co-cultivation of epithelial and lymphoid cells obtained from embryos at the appropriate developmental stage regularly led to agglomerate formation within 48...
Topics
- Animals
- B-Lymphocytes
- Bursa of Fabricius
- Cell Aggregation
- Cell Membrane
- Cell Movement
- Cell Proliferation
- Cells, Cultured
- Chick Embryo
- Chickens
- Cytidine Deaminase