Locus of Enterocyte Effacement from <i>Citrobacter rodentium</i> : Sequence Analysis and Evidence for Horizontal Transfer among Attaching and Effacing Pathogens

Abstract excerpt

The family of attaching and effacing (A/E) bacterial pathogens, which includes diarrheagenic enteropathogenic Escherichia coli (EPEC) and enterohemorrhagic E. coli (EHEC), remains a significant threat to human and animal health. These bacteria intimately attach to host intestinal cells, causing the effacement of brush border microvilli. The genes responsible for this phenotype are encoded in a pathogenicity...

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