Article
Active cytotoxic necrotizing factor 1 associated with outer membrane vesicles from uropathogenic Escherichia coli.
Infection and immunity - 1 Apr 2006
Kouokam J Clavin, Wai Sun Nyunt, Fällman Maria, Dobrindt Ulrich, Hacker Jörg, Uhlin Bernt Eric
Abstract excerpt
Cytotoxic necrotizing factor type 1 (CNF1) is one of the virulence factors produced by uropathogenic Escherichia coli (UPEC). How this toxin is translocated from the bacterial cytoplasm to the surrounding environment is not well understood. Our data suggest that CNF1 may be regarded as a secreted protein, since it could be detected in culture supernatants. Furthermore, we found that CNF1 was tightly associated to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.