Article
Genome wide distribution of illegitimate recombination events in Kluyveromyces lactis.
Nucleic acids research - 1 Jan 2006
Kegel Andreas, Martinez Paula, Carter Sidney D, Aström Stefan U
Abstract excerpt
Illegitimate recombination (IR) is the process by which two DNA molecules not sharing homology to each other are joined. In Kluyveromyces lactis, integration of heterologous DNA occurred very frequently therefore constituting an excellent model organism to study IR. IR was completely dependent on the nonhomologous end-joining (NHEJ) pathway for DNA double strand break (DSB) repair and we detected no other...
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